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Less commonly the leaves are decocted or extracted into water and then evaporated into a tar that can be swallowed. Ultra Enhanced Indo Kratom Dosage kratom is not often smoked although this method does provide some effect. Kratom contains many alkaloids including mitragynine (once thought to
be the primary active) mitraphylline and 7-hydroxymitragynine (which is currently the most likely candidate for the primary active chemical in the plant).
Antidepressant-like effect of mitragynine isolated from Mitragyna speciosa Korth in mice model of depression. Idayu NF Hidayat MT Moklas MA