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There was a distinct threshold for cytotoxicity at doses higher than 11. The IC50 value for MSE cytotoxicity in this cell is estimated as 230.

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The Kratom plant originates from Southeast Asia, and its leaves are harvested to create the Kratom product family. The plant is part of the rubiaceae family, or more.

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Alphanaphtoflavone (bar Injecting Kratom Tincture graph D) also showed some marginal difference in inhibiting the MSE toxicity. Cytotoxicity was apparently unaffected.

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