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Some people are extremely sensitive and others are amazingly resistant to its effects. Somewhere between 10%-15% of people are unusually insensitive. Presumably this is due to differences in individual body chemistry.
Some people like to infuse it into wine and then drink the wine. When prepared this way the herb is mixed with wine and allowed to infuse for anywhere from a few hours to a few weeks. The flowers contain the alkaloids aporphine and nuciferine as well as other related compounds.
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